Research Department

Current Studies

Iowa City Hypertension (High Blood Pressure)

Inclusion:

  • Male or female ages Age ≥ 21
  • Average of last 3 blood pressure readings for Non-Diabetics systolic blood pressure of 140-179 or diastolic blood pressure of 90-109, Diabetics systolic blood pressure of 130-179 or diastolic blood pressure of 80-109
  • Currently on 0-3 blood pressure meds

Exclusion:

  • MI (heart attack) in past 6 months
  • Class III-IV CHF (congestive heart failure)
  • Dementia
  • Systolic blood pressure >180 or diastolic blood pressure >110

Benefits of participation in the study:

  • $100.00 for 3 visits over 6 months
  • Two 24 hour blood pressure readings

Study only open to patients from NEIFPC. If you are interested in this study contact Pam Trenkamp, Study Coordinator, at 319-272-2523

Failed Oral Treatment (Diabetes- Type II) (insulin-Lantus vs Lispro)

Inclusion:

  • Male or female ages 30 thru 79 years
  • At least 90 days of 2 oral meds (at least ½ max dose for both)
  • A1c 7.2%-12%

Exclusion:

  • Prior insulin use
  • Have taken precose, glyset, symlin, byetta, starlix, or prandin in the past 6 weeks

Benefits of participation in the study:

  • $720 for 15 visits over 2 ½ years
  • Free oral diabetic study medications that you are currently taking
  • Free study related medication, labs, ECG's, physicals and diabetic testing supplies

If you are interested in this study contact Angie Bixby-Ellermann, Study Coordinator, at 319-272-2536

Failed Diet/Exercise (Diabetes- Type II) (Metformin vs Avandamet)

Inclusion:

  • Male or female ages 18-75 years
  • Currently treated with diet/exercise only
  • BMI(body mass index) >25
  • A1c ≥ 7.5% to ≥ 10.5% at pre-screening visit

Exclusion:

  • Have taken oral diabetic medication or insulin in the past 6 months for more than 14 days
  • Systolic blood pressure >160, diastolic blood pressure of >90

Benefits of participation in the study:

  • $665.00 for 13 visits over 82 weeks
  • Free study medication, diabetic testing supplies, study related lab work, ECGs and physicals

If you are interested in this study contact Angie Bixby-Ellermann, Study Coordinator, at 319-272-2536

Osteoarthritis

(naproxen vs celecoxib vs ibuprofen, everyone provided with 20 or 40 mg Nexium)

Inclusion:

  • Male or female ≥ 18 years of age
  • Osteoarthritis or rheumatoid arthritis for at least the past 6 months
  • Have required chronic (daily use) of pain medication for at least 6 months
  • Established cardiovascular disease or high risk factors for cardiovascular disease

Exclusion:

  • Acute joint trauma with active symptoms that may interfere
  • Current use of oral corticosteroids(>20 mg prednisone or equivalent per day)
  • History of GI perforation, obstruction or bleeding within last 6 months
  • Cancer in the last 5 years
  • Need for warfarin (Coumadin)

Benefits of participation in the study:

  • $300.00 for 13 visits over 42 months, plus free Nexium
  • Free study medication, study related lab work, physicals and ECG's

If you are interested in this study contact Angie Bixby-Ellermann, Study Coordinator, at 319-272-2536

Bacterial Conjunctivitis (Pink eye) (Placebo vs 0.6% ISV-403)

Inclusion:

  • Male or female ≥ 1 year old
  • Must have clinical diagnosis of acute bacterial conjunctivitis and exhibit purulent conjunctival discharge (crusty/sticky eyelids and redness)

Exclusion:

  • Use of topical ophthalmic solution including tear substitutes within 2 hours of entry to the study
  • Use of antibiotics within 72 hours of entry to the study
  • Ocular surgery in the past 6 weeks

Benefits of participation in the study:

  • $225.00 for 3 visits over 8 days
  • Free study medication, study related lab work

If you are interested in this study contact Pam Trenkamp, Study Coordinator, at 319-272-2523